Pedro-Juan Vázquez Bragan, known professionally as PJ Sin Suela, was born on August 5, 1989, in The Bronx, New York, and raised in Ponce, Puerto Rico. He developed an interest in music from his mother, who played the guitar. He gained a reputation in high school for rapping for his classmates at lunch. He graduated with an MD degree from medical school at Universidad Central del Caribe in 2015, after which he decided to pursue music as a career. He initially began performing with the plan of only doing so for a year, but noticed that the money he generated from his performances allowed him to pay his rent. He has since stated that after the success of his career, he "doesn't see himself in a hospital" but plans to give educational classes and lectures about medicine. However, he has since returned to the medical field due to the COVID-19 pandemic, working in the Hospital San Cristóbal in Ponce. His music often discusses social and political themes, and one of his goals as an artist is to "make a positive social change in the world".